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Date Submitted: 12/11/07
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Researchers Unlock Secrets of Anti-Cancer Gene



Added by Bryan

Description: Researchers think they have discovered how to boost one of the body's natural cancer fighters.

It might be possible to superpower the gene, known as PTEN, by tinkering with an enzyme that regulates its activity, scientists report in the Jan. 12 issue of Cell.

Although they are a long way from developing an actual drug based on the discovery, the ability to manipulate the tumor-suppressor gene is "potentially a real breakthrough," said study author Dr. Pier Paolo Pandolfi, a professor of cancer biology and genetics at Memorial Sloan-Kettering Cancer Center.

Pandolfi and other researchers at Sloan-Kettering and Columbia University were intrigued by the PTEN gene, which suppresses

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