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Date Submitted:
12/11/07
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Gene Therapy Reverses Erectile Dysfunction in Rats
Description:
SUNDAY, June 3 (HealthDay News) -- Gene therapy using nerve growth factors reversed erectile dysfunction in rats within four weeks, say University of Pittsburgh School of Medicine researchers.
Erectile dysfunction (ED) affects between 15 million and 30 million men in the United States. Many men suffer nerve damage-related ED after surgery for prostate cancer. The Pittsburgh team found that the genes for the "glial cell line derived neurotrophic factor" (GDNF) and the GDNF family ligand, called neurturin, were both effective in treating erectile dysfunction in the rats. The genes were placed in a genetically engineered herpes simplex virus, which was then injected into the rats' damaged cavernous nerve. The finding suggests a potential new treatment Read the Complete Article Similar content: High Dose Radiation for Prostate Cancer Won't Raise Sexual Dysfunction, in Prostate Cancer In Vivo Evidence for Microvascular Oxidative Stress in Spontaneously Hypertensive Rats, in Hypertension Mineralocorticoid Blockade Reduces Vascular Injury in Stroke-Prone Hypertensive Rats, in Hypertension Basics of ACTH therapy, in Epilepsy New Therapy for Partial Paralysis, in Stroke |
