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Date Submitted:
12/11/07
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Gene Holds Key to Blood Stem Cells
Description:
THURSDAY, July 26 (HealthDay News) -- A gene named Sox17 appears to regulate the development of blood-forming stem cells in fetal mice, new research shows.
In fact, fetal mice who could not produce their own blood cells did just that after they were given cells that contained Sox17, say researchers at the University of Michigan. Reporting in the July 26 issue of Cell, the researchers said their results point to an important difference between adult and fetal stem cells, since Sox17 does not assist in regrowing blood cells in adult mice. "Identification of Sox17 could also facilitate efforts to form blood-forming stem cells from human embryonic stem cells, a goal that could enhance bone marrow transplantation," lead author Injune Kim said in a prepared statement. The finding may one day have implications for the treatment of childhood leukemia, where blood-making cells are disrupted. "One of the next questions in our crosshairs is whether Sox17 gets inappropriately activa Read the Complete Article Similar content: Study Tests Blood Stem Cells to Boost Immune System, in Leukemia Stem Cells Restore Memory in Mice, in Alzheimers Scientists Find Way to Track Stem Cells in Brain, in Multiple Sclerosis Adult Stem Cells Found in Hair Follicles, in Multiple Sclerosis Scientists Find Cancer Stem Cells in Pancreatic Tumors, in Leukemia |

