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Prostate Cancer
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Definition of Prostate Cancer
Prostate cancer is a disease in which cells in the prostate gland become abnormal and start to grow uncontrollably, forming tumors.
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Obese Men More Likely To Die From Prostate Cancer
A study released this week revealed that men who are overweight or obese at the time of diagnosis are nearly twice as likely to die from locally advanced prostate cancer as patients who are of normal weight. The study was conducted by Dr. Jason Efstathiou and a group of his colleagues from Massachusetts General in Boston.
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Prostate Cancer Difficult To Detect In Obese Men
A new study suggests that PSA levels in obese men may be falsely interpreted as low, causing delays in diagnosis and treatment. The study, conducted by Duke Prostate Cancer Center researchers, noted that obese men have more blood circulating in their bodies than normal weight men, and as a result the concentration of prostate-specific antigen, or PSA, in the blood can become diluted.
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Red Wine May Help Prevent Prostate Cancer
Resveratrol, a compound found in red wine, may help prevent the development of prostate cancer. These are the results of a study conducted at the University of Alabama at Birmingham (UAB).
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Omega-3 Fatty Acids May Slow Prostate Cancer Growth
Research in mice suggests that a diet high in omega-3 fatty acids found in fish oil and certain types of fish could potentially improve the prognosis of men who are genetically prone to develop prostate cancer.
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Treatment Beats Watchful Waiting for Older Prostate Cancer Patients
Aggressive treatment of early prostate cancer, and not watchful waiting, improves the survival of older men, a new study suggests. "There has been a belief that watchful waiting was the safest treatment for older men with moderate prostate cancer," said Dr. Yu-Ning Wong, an oncologist at Fox Chase Cancer Center who is lead author of the report in the Dec. 13 issue of the Journal of the American Medical Association. "Our study suggests there may be a survival benefit," Wong said.
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Clinical Trials Update: Dec. 18, 2006
Non-Small Cell Lung Cancer
Prostate Cancer
Parkinson's Disease
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Breast Cancer Stem Cells Seem to Survive Radiation Therapy
Breast cancer stem cells, a type of cell that scientists have recently discovered is difficult to kill, may be especially resistant to radiation therapy, a new study suggests. In fact, the radiation can even increase the growth of these stubborn stem cells, report researchers from the University of California, Los Angeles, David Geffen School of Medicine.
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Prostate Treatment Costs Substantial and Sustained
The average five-year cumulative cost of prostate cancer management in the United States is $42,570, a new study says. Treatment choices were influenced by patients' age and disease risk. Older, high-risk patients often required more expensive treatments, such as external beam radiation and androgen deprivation therapy. Younger, lower risk patients often required the less costly prostatectomy, the study said.
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Excess Weight Boosts Risk of Death From Prostate Cancer
Prostate cancer patients who are overweight or obese are at higher risk of dying from their illness, a new study reveals. The researchers did not, however, find a connection between being obese and developing the disease in the first place. "Even though we didn't find that obesity increases the risk of developing prostate cancer, we did find that it does actually increase the risk from dying from it, so this study really sheds more light on the obesity connection," said lead author Margaret E. Wright, a research fellow with the division of Cancer Epidemiology and Genetics at the National Cancer Institute.
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Researchers Unlock Secrets of Anti-Cancer Gene
Researchers think they have discovered how to boost one of the body's natural cancer fighters.
It might be possible to superpower the gene, known as PTEN, by tinkering with an enzyme that regulates its activity, scientists report in the Jan. 12 issue of Cell.
Although they are a long way from developing an actual drug based on the discovery, the ability to manipulate the tumor-suppressor gene is "potentially a real breakthrough," said study author Dr. Pier Paolo Pandolfi, a professor of cancer biology and genetics at Memorial Sloan-Kettering Cancer Center.
Pandolfi and other researchers at Sloan-Kettering and Columbia University were intrigued by the PTEN gene, which suppresses
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Prostate Surgery Is Viable Option for Older Men
Surgery for prostate cancer can be safe and worthwhile for older men above the traditional cutoff age of 70.
That's the conclusion of emerging research that calls into question the traditional view that men should be denied the surgery based on advanced age alone.
Dr. Shabbir M.H. Alibhai, a scientist at University Health Network and the Toronto Rehabilitation Institute in Canada, published a study last year evaluating the effect of radical prostatectomy -- removal of the prostate gland -- among more than 11,000 men in Ontario. The finding: In otherwise healthy older men up to age 79, the risk of death after this surgery is relatively low.
Alibhai thinks the study, because it was carefully done and included a large sample size, is beginning to change medical practice.
"We are finding surgeons are less cautious in thinking about this surgery for men over age 70," said Alibhai. "People are being a little bit more scientific about this thing
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Tomato-Broccoli Combo May Protect Against Prostate Cancer
Broccoli and tomato -- two vegetables known to help fight cancer -- are more effective against prostate cancer if they're eaten together as part of a daily diet than if they're eaten alone, a new study with rats suggests.
University of Illinois researchers fed a diet containing 10 percent broccoli powder and 10 percent tomato powder to a group of rats that had been implanted with prostate cancer cells. Other groups of rats received either tomato powder or broccoli powder alone; a supplemental dose of lycopene (the red pigment in tomatoes believed to be an anti-cancer agent); or finasteride, a drug prescribed for men with enlarged prostates. Another group of rats was castrated.
After 22 weeks, the researchers found that the combined tomato/broccoli diet was the most effective at prostate tumor reduction. Of the other treatments, castration was the only one that came close to being as effective.
"When tomatoes and broccoli are eaten together,
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Scientists Explore Virus-Prostate Cancer Link
Scientists are unraveling the secrets of a virus found in prostate cancer patients that might spur the disease.
In a new study, a U.S. team of researchers says the virus appears to be an infectious retrovirus with the ability to hijack body cells. Retroviruses are a family of viruses that include HIV.
There's no indication yet that the virus could cause or worsen prostate cancer, but the study authors are intrigued by the prospect.
"We have a long way to prove that it's a cause-and-effect, but it's a possibility," said study co-author Robert H. Silverman, a professor and researcher at the Cleveland Clinic. "Another question is whether the virus is associated with other kinds of cancer besides prostate cancer."
It's not uncommon for contagious
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U.S. Cancer Deaths Drop for 2nd Year in a Row
The number of cancer deaths in the United States has dropped for the second year in a row, the first such decreases since researchers started keeping national statistics more than 70 years ago. The most recent decline was much larger than the year before with 3,014 fewer deaths reported between 2003 and 2004, compared to 369 fewer deaths from 2002 to 2003.
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