Low-Dose Aspirin Won't Help Aging Brain
Despite earlier hopes, regular use of low-dose aspirin does not protect older, healthy women against cognitive decline, a major new study concludes. The findings may lay to rest the notion that aspirin can prevent age-related shortfalls in memory and thinking.
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Scientists Restore Lost Memory in Alzheimer's-Like Mice
In a new study, mice bioengineered to mimic the fading memory of Alzheimer's patients got their memories restored -- either by being placed in stimulating environments or by receiving a drug most commonly used to fight cancer.
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Cholesterol-Lowering Drug Aids Memory in Alzheimer's-Like Mice
The cholesterol-lowering statin drug simvastatin (brand name Zocor) boosted memory in mice genetically bred to have an Alzheimer's-like disease, according to a new study. While the drug boosted the mice's spatial memory -- helping them navigate a water maze -- male mice showed the most improvement, according to Dr. H.A. Morcos, chair of pharmacology at the University of Antigua, and colleagues at Florida A&M University.
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High Calcium, Vitamin D Intake May Harm Aging Brain
Seniors who consume high levels of calcium and vitamin D are much more likely to have larger brain lesions that can lead to cognitive impairment, depression or stroke, new research reveals.
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Hormone Therapy May Protect Against Alzheimer's
Women who start hormone therapy earlier in life -- before they turn 65 -- could cut their risk of developing Alzheimer's or another dementia, a new study suggests. This stands in contrast to findings on using hormone replacement therapy (HRT) after age 65, which appears to increase the risk of dementia.
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Certain ACE Inhibitors Cut Elderly Dementia Risk
Certain types of ACE inhibitor hypertension drugs may help cut the risk of dementia in older adults, say researchers at the Wake Forest University School of Medicine. They analyzed data from the long-term Cardiovascular Health Study of almost 5,900 people over age 65 in the United States.
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EEG Works at Spotting Early Alzheimer's
Electroencephalogram (EEG), an 80-year-old technology that measures brain activity, offers a highly accurate means of diagnosing early Alzheimer's disease, a team of U.S. researchers report. The new study was conducted by scientists at Rowan University in New Jersey, the University of Pennsylvania School of Medicine, and Drexel University.
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Blood Marker Could Point to Alzheimer's Risk
Scientists have zeroed in on blood biomarkers that could someday help doctors predict who's at risk for Alzheimer's disease. They might even help guide treatment, the U.S. researchers added. These biomarkers, called cytokines, are all hallmarks of heightened inflammatory responses. Cytokines specific to Alzheimer's disease were found in greater numbers on white blood cells called mononuclear cells.
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Cancer Drugs Appear to Boost Long-Term Memory
Anti-cancer drugs called histone deacetylase (HDAC) inhibitors improved long-term memory and strengthened neural connections in the brains of mice, says a University of California, Irvine, study. The findings suggest that HDAC inhibitors may prove useful in treating people with Alzheimer's and certain other brain diseases, the researchers said.
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Study Probes Role of Stroke, Head Trauma in Alzheimer's
Stroke and head injury trigger a cellular chain of events that increases the risk of Alzheimer's disease, a new study says. Learning more about this process could help in the development of treatments to protect against Alzheimer's disease.
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New Medication Slows Rare Kidney Disease
Researchers say a drug called eprodisate can slow a rare but toxic buildup of amyloid protein that results in end-stage kidney disease. While not a cure for the condition, called amyloid A amyloidosis, the drug can delay the need for kidney dialysis, according to the report in the June 7 issue of The New England Journal of Medicine.
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New Imaging Techniques Hold Promise for Variety of Diseases
New ways of imaging the heart, the brain and the pelvis could lead to better diagnosis and treatment of illnesses such as heart disease, Alzheimer's disease and ovarian cancer. That's the assessment of a series of studies presented this week at the Society for Nuclear Medicine's annual meeting in Washington, D.C.
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U.S. Study Pits an Omega-3 Against Alzheimer's
U.S. researchers have launched a study to examine whether an omega-3 fatty acid called docosahexaenoic acid (DHA) can help slow the progression of Alzheimer's disease. The 18-month clinical trial will be conducted at 52 sites across the United States and will seek to enroll 400 people, age 50 and older, with mild to moderate Alzheimer's disease. The trial is supported by the National Institute on Aging (NIA).
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Better Education Spurs Alzheimer's Patients to Try Risky Treatments
Alzheimer's disease patients who have a better understanding of their condition seem to be more willing to accept potentially risky treatments, a U.S. study finds. Researchers at the University of Pennsylvania interviewed 34 people with mild to moderate Alzheimer's who lived in the community. The patients were asked if they would want to take medications that would delay the progression of Alzheimer's for one year.
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